It also causes a reaction in some people that leads to swollen glands and other serious health problems. Get medical help right away if you have signs of this reaction, like fever, rash, swollen glands, chills, or trouble breathing.
Narcolepsy
Narcolepsy causes sleepiness during the day and problems sleeping at night. People with this condition also have trouble staying awake at work, in school, or while driving. They often have memory lapses and find it difficult to concentrate. It’s also a risk factor for depression, and disrupted sleep can worsen existing mental health conditions. People with narcolepsy are at higher risk of mental health issues and can be stigmatized, so it’s important to see a therapist if you have symptoms. You can also join a support group to discuss your symptoms with others.
Modafinil Online can help people with narcolepsy stay awake and alert. It can also boost your cognitive performance, especially if you’re tired or stressed. But it’s important to take it with a prescription from your doctor to avoid side effects.
Modafinil increases dopamine levels in the brain. It has also been shown to enhance learning processes in mice. It has also been shown to improve performance on tasks that require concentration and attention in healthy people.
Modafinil interacts with over 35 different drugs, so it’s important to check with your doctor or pharmacist before taking any other medications. Taking modafinil with certain other medicines can increase the chances of serious side effects, such as severe rash or angioedema (blushing and swelling of the face or lips). It also affects the way your body absorbs other medicines that are taken orally.
Obstructive sleep apnea
Obstructive sleep apnea happens when you have an obstruction or blockage of your airway during your sleep. This can lead to a lack of oxygen in your blood, which can cause health problems.
Modafinil has been shown to reduce obstructive sleep apnea in a few studies and may improve the quality of life for people with this condition. It's important to talk with your doctor about your risk factors and get the right treatment for your obstructive sleep apnea.
Studies of cognition show that single-dose modafinil increases accuracy on the Wisconsin Card Sorting Test and reaction time (RT) on the Stroop Color-Word Interference Task, compared to placebo. These effects are largely due to elevations in extracellular monoamines, including a and b adrenergic receptors and DA receptors. The arousal and activity-promoting effects of modafinil are also mediated by catecholamine systems, including dopamine and norepinephrine.
Modafinil has been found to reduce fatigue and sedation in several neurological and medical conditions, including multiple sclerosis, idiopathic Parkinson's disease, chronic fatigue syndrome, and post-anesthetic sedation. However, the results have been mixed, and more research is needed to understand why some people respond better than others to this drug.
Shift work sleep disorder
People with shift work sleep disorder have difficulty adjusting to their regular sleep schedules, resulting in impaired performance on the job. They experience fatigue, trouble concentrating and remembering things during the day, and poor quality sleep during night shifts. Shift work sleep disorder may also affect a person's health and mood.
Medications such as modafinil (the brand name Provigil in the United States) and Modalert Tablet (2-[(diphenylmethyl) sulfinyl] acetamide) can help to decrease shift work sleep disorder. These medications are in a class of drugs called wakefulness-promoting agents and have been shown to improve alertness and reduce daytime fatigue in some clinical trials. Modafinil is a nonamphetamine stimulant and has not been associated with the side effects of amphetamines. It is not known exactly how modafinil promotes wakefulness. At pharmacologically relevant concentrations, it does not bind to most potential targets involved in the sleep/wake system, such as adenosine, dopamine, norepinephrine, GABA, histamine-3, and melatonin.
The best treatment for shift work sleep disorder is to change work hours or find a different type of employment. If this is not possible, a healthcare provider can help with other options. These can include lifestyle changes such as consuming small amounts of caffeine early in the morning on shifts, using light to help regulate the circadian rhythm avoiding napping during shifts, and taking steps to ensure that a person gets adequate rest at home.
Other conditions
Modafinil is used to treat several neurological and medical conditions that cause excessive daytime sleepiness, such as multiple sclerosis, idiopathic Parkinson’s disease, chronic fatigue syndrome, fibromyalgia, obstructive sleep apnea, and post-anesthetic sedation. It has also been studied for its effects on cognitive dysfunction in neuropsychiatric disorders, such as treatment-resistant depression and attention-deficit/hyperactivity disorder (ADHD).
Although it’s not known exactly how modafinil works, it seems to prevent nerve cells from reabsorbing dopamine, an excitatory chemical, after it is released into synapses. This keeps brains active and can improve performance on cognitive tests. In one small study, doctors who took the drug before work performed better than those who didn’t. However, it’s unclear if this effect is permanent, and the drug hasn’t been shown to make people less tired after they stop taking it.
While it’s a safe drug for most adults, modafinil can increase the risk of heart problems in people with coronary heart disease or diabetes. It can also interact with several medications, including cimetidine, clozapine, nefazodone, and phenytoin. It can also increase the risk of a serious skin reaction, called Stevens-Johnson syndrome or toxic epidermal necrolysis.
In Australia, modafinil is a Schedule 4 prescription-only medicine and should be bought only under the instruction of a medical professional. Buying it online without a prescription is illegal and can put your health at risk. If you suspect an unauthorized sale, contact the TGA.
