Let's have a deeper check out of the stats, equipment, and skills you will need to make the best Assassin build for clearing Ubers and beyond.
Gear
The gear you will need for this build includes Dual Mosaic Claws, Flickering Flame headgear, Mara's Kaleidoscope amulet, Enigma armor, Dracul's Grasp gloves, Bul-Kathos' Wedding Band ring, Arachnid Mesh belt, Raven Frost ring, and Gore Rider boots. To round out your build, you will also need skillers, small charms, a Torch, as well as an Annihilus. You'll find that this build requires not particularly expensive gear, which makes it easy to acquire.
Weapon: Dual Mosaic claws
Helmet: Flickering Flame
Amulet: Mara's Kaleidoscope
Armor: Enigma
Gloves: Dracul's Grasp
Belt: Arachnid Mesh
Rings: Raven Frost ring
Boots: Gore Rider
Stats
After equipping all gear, you will need the following stats:
Strength:156
Dexterity:85
Vitality: Remaining
Energy:70
Skills
The skills you will need to invest in are:
Martial Arts:
Level 20 Fist of Fire,
Level 20 Claws of Thunder,
Level 20 Tiger Strike,
Level 20 Phoenix Strike,
Level 20 Blades of Ice,
Level 1 Cobra Strike,
Level 1 Dragon Talon
Shadow Discipline
Level 1 Claw Mastery, Level 1 Weapon Block, Level 1 Burst of Speed
You should concentrate on getting five of the Martial Arts skills to level three and invest a place into Burst of Speed and Weapon Block with a place in Dragon Talon.
Mercenary
For the Mercenary, you will want Infinity, Fortitude, and Andariel's Visage. These items will require your build towards the highest level and let you tackle Ubers effortlessly.
Gameplay
Tiger Strike and all sorts of the previous Charge-up Skills now only need a single charge per Finisher move, producing a lot more damage overall. With Mosaic in play, no Charges have to be consumed, meaning you can just continue slaying the whole time.
Dragon Tail may be the finisher of preference, using its powerful kick bolstered by Fire Damage. For single-target damage, the Crushing Blow and Physical Damage in the build will require away huge HP pools effortlessly.
Alternative Gear and Stats
Given this build is mid-range, it won't be very expensive to accomplish if you are not min/maxing the things in each slot. However, for people who have accrued hardly any assets, here are a few lower cost, alternatives that may be considered (note given your mobility with Dragon Flight, Enigma is not a must-have):
Weapon:
Bartuc's Cut-Throat: A unique Greater Talons providing you with +1 to Martial Arts Skills, +2 to Assassin Skills, 20% possibility of Deadly Strike, or more to +150% Enhanced Damage. It also includes a chance to cast a level 6 Fade when struck.
Natalya's Mark: A unique Scissors Suwayyah providing you with +200% Enhanced Damage, +200% Damage to Demons, +200% Damage to Undead, and +3 Assassin Skills. It also includes a chance to cast level 20 Mind Blast when struck.
Armor:
Chains of Honor: A powerful runeword that may be made by combining the runes Dol and Um inside a 4-socketed armor. It provides +2 to any or all skills, +200% Enhanced Defense, +70 to Life, +65 to any or all Resistances, and 8% Life stole per hit.
Guardian Angel: A unique Templar Coat providing you with +200% Enhanced Defense, +20 to Strength, +30% Faster Block Rate, and +15 to Maximum Resistance. It also converts 25% of Physical Damage to Magic Damage.
Gloves:
Dracul's Grasp: A unique Vampirebone Gloves providing you with +10 to Strength, +15 to Life, 5-10% Life stolen per hit, and a 10% Chance of Open Wounds. It also includes a chance to cast Life Tap on striking.
Lava Gout: A unique Battle Gauntlets providing you with +20% Increased Attack Speed, +1 to Maximum Damage, +25 to Maximum Fire Resist, and 10-20% Enhanced Defense. It also adds Fire Damage to attacks.
Boots:
Gore Rider: A unique War Boot providing you with a +30% Faster Run/Walk, 15% Chance of Crushing Blow, +20 to Maximum Damage, and 10% Chance of Open Wounds. It also adds Deadly Strike to attacks.
Sandstorm Trek: A unique Scarabshell Boot providing you with +20% Faster Run/Walk, +20% Faster Hit Recovery, +20 to Strength, +20 to Vitality, or more to 15% Damage Reduced.
Belt:
Thundergod's Vigor: A unique War Belt providing you with +10 to Maximum Lightning Resist, +20 to Strength, +20 to Vitality, 5-10% Life stolen per hit, or more to 10% Chance to Cast Level 3 Chain Lightning on Attack. It also adds Lightning Damage to attacks.
A string of Ears: A unique Demonhide Sash providing you with Damage Reduced by 10-15%, +15 to Maximum Stamina, or more to 8% Life stolen per hit.
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